Myriads program web page

Departamento de Bioquímica, Genética e Inmunología
Área de Genética. Universidad de Vigo


Myriads: p-value-based dependence detection, simulation, and multiple testing correction

Myriads (formerly SGoF+) is a software package for p-value-based multiple testing that also implements a dependence test and p-value simulation. Myriads performs very well under high-dimensional biological data, easily managing hundreds of thousands of p-values. The Myriads software is implemented for Windows and Linux and includes multiple testing correction methods as FWER-based methods SGoF, Bonferroni, sequential Bonferroni and Hommel, and the Benjamini-Hochberg (BH), Benjamini and Yekutieli (BY), Benjamini, Krieger and Yekutieli (BKY) FDR-based methods, a modified sliding linear model (SLIM) and Bon-EV methods, and the permutation-based maxT; jointly with different q-value estimation algorithms (see Methodology section). A MATLAB version of the SGoF algorithm was developed by Garth Thompson from M.I.N.D. Lab, Georgia Institute of Technology and Emory University, and is available here.







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